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Cyclodextrins and their complexes chemistry, analytical methods, applications

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Published by Wiley-VCH in Weinheim .
Written in English


  • Cyclodextrins.

Book details:

Edition Notes

Includes bibliographical references and index.

Statementedited by Helena Dodziuk.
ContributionsDodziuk, Helena.
The Physical Object
Paginationxvii, 489 p. :
Number of Pages489
ID Numbers
Open LibraryOL18266632M
ISBN 103527312803

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Cyclodextrins and Their Complexes Edited by Helena Dodziuk Cyclodextrins and Their Complexes. Cyclodextrins and Their Inclusion Complexes. Dominique Duchêne. UMR CNRS , Physico‐Chimie‐Pharmacotechnie‐Biopharmacie, Université Paris‐Sud, Châtenay, Malabry, France. Book Editor(s): Erem Bilensoy. Hacettepe University, Ankara, Turkey. Search for Cited by: By the mids, each of the natural cyclodextrins had been structurally and chemically characterized and many more complexes had been studied. Since the s, extensive work has been conducted by Szejtli and others exploring encapsulation by cyclodextrins and their derivatives for industrial and pharmacologic applications. Cyclodextrins are cyclic oligosaccharides which are made up of six to eight glucopyranoside units attached by glucosidic bonds at C1 and C4. Cyclodextrins are capable of forming inclusion complexes with other molecules due to their toroidal shape which is largely hydrophobic.

The cover of Friedrich Cramer's book "Einschlussverbindungen" (inclusion compounds), published in Berlin in In this book Cramer describes various types of compounds that are able to form. The kind of information on CyDs and their complexes that can be provided by NMR studies is discussed in Chapter 9 while Chapter 10 is devoted to the application of other physicochemical methods (UV, circular dichroism, mass spectroscopy, electrochemistry, AFM and STM, etc.) to the elucidation of the structure of CyDs and their complexes. Cyclodextrins (CDs) are cyclic oligomers of α-1,4-linked D -glucopyranose. Due to their unique structure, marked by a chiral and hydrophobic cavity, CDs have been extensively used as chiral selectors and drug delivery systems.   Although cyclodextrins (CDs) have been studied for over years and can be found in at least 35 pharmaceutical products, they are still regarded as novel pharmaceutical excipients. CDs are oligosaccharides that possess biological properties that are similar to their linear counterparts, but some of their physicochemical properties differ.

  Offering comprehensive and up-to-date know-how in one compact book, an experienced editor and top authors cover every aspect of these important molecules from molecular recognition to cyclodextrins as enzyme models. A variety of cyclodextrin-based molecular structures, with substitutions of either primary or secondary faces of the natural oligosaccharide macrocycles of α-, β-, or γ-cyclodextrins, have been designed towards innovative applications of self-assembled cyclodextrin nanomaterials. Amphiphilic cyclodextrins have been obtained by chemical or enzymatic modifications of their macrocycles using.   Cyclodextrins are natural oligosaccharides obtained from starch. They were discovered in by Villiers, and attracted major scientific and industrial interests from the late s. Actually, cyclodextrins are among the most remarkable macrocyclic molecules with major theoretical and practical interest for chemistry and biology. Szejtli, J. () Cyclodextrins and Their Inclusion Complexes. Akadémiai Kiadó, Budapest. has been cited by the following article: TITLE: Spectrofluorometric Study of the Inclusion Complexation of Fluorescent Whitening Agents and β-Cyclodextrins.